孫慧慧，女，工學博士，副研究員，2016年1月份畢業于華東理工大學生物化工專業。主持包括國家自然科學基金青年基金、中國博士后科學基金、山東省自然科學基金博士基金等在內共計6項課題，并作為科研骨干參與了國家重點研發計劃“藍色糧倉科技創新”重點專項1項。累計發表論文20余篇，其中以第一作者在Comprehensive Reviews in Food Science and Food Safety、Journal of Agricultural and Food Chemistry、International Journal of Biological Macromolecules等領域內權威期刊發表論文7篇；獲授權發明專利6項；參編著作《海洋食品酶工程》1部。榮獲神農中華農業科技獎科學研究類成果一等獎（第五完成人，2021）。黃海水產研究所“優秀博士后”稱號（2017）。
主要研究領域為微生物酶與生物催化轉化在海洋食品中的應用，主要包括酶的基因發掘和高效表達，催化機制解析和理性分子改造，生化反應過程優化與調控等研究。
代表性論文
[1] H.H. Sun, L. Gao, C.H. Xue, X.Z. Mao*. Marine-polysaccharide degrading enzymes: Status and prospects. Comprehensive Reviews in Food Science and Food Safety. 2020, 19, 2767-2796.
[2] H.H. Sun, G.S. Yang, R. Cao*, X.Z. Mao, Q. Liu. Expression and characterization of a novel glycoside hydrolase family 46 chitosanase identified from marine mud metagenome. International Journal of Biological Macromolecules. 2020, 159, 904-910.
[3] H.H. Sun, X.Z. Mao, N. Guo, L. Zhao, R. Cao*, Q. Liu. Discovery and characterization of a novel chitosanase from Paenibacillus dendritiformis by phylogeny-based enzymatic product specificity prediction. Journal of Agricultural and Food Chemistry. 2018, 66, 1139-1145.
[4] H.H. Sun, R. Cao, L.H. Li*, L. Zhao, Q. Liu. Cloning, purification and characterization of a novel GH46 family chitosanase, Csn-CAP, from Staphylococcus capitis. Process Biochemistry. 2018, 75, 146-151.
[5] G.S. Yang, H.H. Sun, R. Cao*, Q. Liu, X.Z. Mao*. Characterization of a novel glycoside hydrolase family 46 chitosanase, Csn-BAC, from Bacillus sp. MD-5. International Journal of Biological Macromolecules. 2020, 146, 518-523.
[6] H.H. Sun, W.Y. Gao, H.L. Wang*, D.Z. Wei. Expression, characterization of a novel nitrilase PpL19 from Pseudomonas psychrotolerans with S-selectivity toward mandelonitrile present in active inclusion bodies. Biotechnology Letters. 2016, 38, 455-461.
[7] H.H. Sun, Hualei Wang*, Wenyuan Gao, Lifeng Chen, Kai Wu, Dongzhi Wei. Directed evolution of nitrilase PpL19 from Pseudomonas psychrotolerans L19 and identification of enantiocomplementary mutants toward mandelonitrile. Biochemical and Biophysical Research Communications. 2015, 468, 820-825.
[8] H.H. Sun, W.Y. Gao, H.Y. Fan, H.L. Wang*, D.Z. Wei. Cloning, purification and evaluation of the enzymatic properties of a novel arylacetonitrilase from Luminiphilus syltensis NOR5-1B: a potential biocatalyst for the synthesis of mandelic acid and its derivatives. Biotechnology Letters. 2015, 37, 1655-1661.
